I use a ,243 off and on for deer hunting. All the deer (3-4) I have shot with the .243 have been with 85 grain Nosler Partitions. Thye have all ran 20-50 yards after heart/lungs shots. The shots have ranged between 44 and 110 yards.
I probably would try the 85 grain Barnes TSX if I used the rifle more, I carry a 7mm-08 or a .30-06 more often.
Will