"2) I am getting to old to track an animal all over God's Creation"
Then rule #1 should be practice enough to hit them in the right spot. Regardless of bullet type. There are many great bullets on the market and you will hear good and bad about all of them. I am a firm believer the bullets out in the marketplace today will do the job if the shooter does theirs. I have heard the first hand accounts, but struggle to believe a perfectly double lunged deer or heart shot animal goes more then 100 yards.
I have shot the Powerbelts 245 gr Aerotips out of my .50 cal CVA Kodiak Mag sitting on 2 50 gr pellets of 777. Ranges varied from 15 yards out to about 110. All were passthrough shots and the deer never made it passed 60 yards. I have has the same results with TC Shockwaves in my Triumph.
All that being said, find the bullet your gun likes the best, shoots the most accurately and put the bullet in the kill zone. Good luck and keep us informed.