Best bullet is either A-frames, TBBC, failsafes, or the best is X. Partitions will also get the job done with ease. Ones that might not is gamekings, about anything hornady makes, BT's, etc.
Go with the TSX, you won't be disappointed. I have shot 3 deer with accubonds, and got complete penetration on all, but I can guantee you TSX will laser thru just about any shoulder.