Some of the biggest racked bucks I've ever seen came from the river bottoms of the Ohio.
Even if it hasn't been dry in your area,bucks will be located near the river water sources. Get in there ASAP to locate where the big boys are using the water to come to,and check out where they seem to be coming from.
For one thing, the land seems to be more fertile and the water speaks for itself. I'd get inbetween a bedding area and the river and way-lay one coming to the water in the evening. Also,my scouting would be taking place now, as to not disturb any summer patterns they're on now,because come opening day bow season,they should be in the general vicinity.
Let us know how your scouting and season goes ... sounds like you have a hot area to hunt!