Been using the Barnes 50 grain X-bullet, Danzac coated by myself...very very little pelt damage..similar to a FMJ but it always passes right on out the other side and will bust any bone or shoulder shield it hits..big game bullets on coyotes, interesting change..problem, it get's a little expensive but every pelt can be sold which more than pays in the long run..oh yeah, out of a .22/250 around 3700 fps..it'll reach out an touch em' and penetrate em' from any angle...