I think one of the biggest errors people make when sighting in is they seem too quick to start moving the scope or sights. If that rifle will not shoot a good group at a moderate distance like 25 or 50 yards, I sure would not expect better at 100 yards. One trouble of course is, some ranges do not offer closer distances. But until I actually work up a solid good shooting load, I am not touching the sight or scope.

I just started sighting in a Genesis. I was using 50 yards. But it would not have been uncommon for me to try 25 even 13 yards. In fact when I mount the scope on the rifle I will probably do my first shooting at 13 yards. If the group is basically a hole at that distance it tells me that the load is working good, and the scope is holding. I then adjust dead to the bull. It would surprise you what happens when you back up to 100 yards without moving that scope hairs. It is real close.

I noticed also you are shooting Superglide sabots. A question... does your rifle load real hard with the regular Shockwave sabots? Sometimes you can get too loose a sabot and it will cause the rifle to spray a little. That might be what you're experiencing. If you have some of the short MMP sabots in .452 around, try switching the Shockwaves into them and shoot a group with 110 grains of BlackHorn 209 just to see what happens. A tighter sabot means a tighter seal, and with Blackhorn that is important.