RE: I defer to more knowledgable people
I once read that Jim Shockey ... a well know sports writer hunted all the large game animals for years with a Knight Rifle (I believe it was a disc rifle). If I remember from my reading,his load was 100 grains of Pyrodex RS and a 300 grain Nosler Partition. With that load he took moose, all the great bears, elk, sheep, etc.
Sabotloader has shown the knock down power of the Nosler bullet. I have not shot an animal with the Nosler yet, but I can also state.. they are one of the most accurate bullets I have ever shot.
Now the Dead Center I am sure is a good bullet. Is this a pure lead bullet? If it is, you have to take into consideration how well this bullet will expand, and hold together. We know from photos and in the field experience how the Nosler is known for its ability to stay together and mushroom perfect.
Also you need to consider how the accuracy of each is. I do not think that 40 grains in bullet weight would make me lean the other way. I would look at accuracy, bullet construction, expansion ability, and penetration ability. Also I some times see numbers posted of what a bullet will do, and kind of hate to base any decision on that fully. Personally I would go with the Nosler...