RE: 22-250 on Deer
When you start a thread on 22.250's and deer, you are gonna get peoples opinions, like it or not. I have never taken a deer with a 22.250, butI was there when my buddy dropped a small buck in Oklahoma. It was a heart shot and the buck dropped like a rock. I don't remember what kind of round he had, but I know it was factory.
There are deer and there are big deer. For smaller deer in the south a 22.250 is fine. I wouldn't use it, but I know quite a few guys that do, and they have been very successful.
Far the larger northern bruisers and mule deer, a .243 would be my minimum, but a .270 would be my choice.