My experience has been to go with a 165 gr. over a 150. What you gain in velocity cannot overcome what is lost in bc. 150gr bullets also do not penetrate on deer sized game at this range very well either, although it will work I only had one hit at 430yards that had an exit wound, granted this was using some handloads with Nosler BT's and not with a Barnes X type bullet which would probably deliver much better down range performance.