I voted "heart-lung only" but only b/c thats the closest answer to my feelings.
I will always take the heart-lung shot when presented with it, but if not and a different shot presents itself, i have to weigh the odds and options before I decide to not shoot. I have passed on dozens of neck shots but have taken and successfully made 2 of them. Definitely not my first choice but was able to see the shot and deem it ok under the circumstances. Also, took one pretty high neck shot that could also be called a head shot. It was actually a high neck shot that entered low behind the ear of a little doe on the last day of the season. It was less than 40 yards, using a 4X scope, standing still quartering slightly away. I held for a while and thought for a while but ultimately made the shot. Dad needed some venison in the freezer and I would have taken the same shot on a larger deer but this was all that was offered that season.

I usually pass on any shot that doesn't make me feel I can pull it off safely for the woods around me and the animals' quick demise, but always look for and hold out for a heart-lung type shot.