Have shot Hoyt's since the late 80's. Just purchased my first Mathews in Sept. It was the Drenalin after shooting the Vectrix, PSE X-Force and Drenalin one after the other. In my opinion, the Drenalin out performed the other two that day and is why I chose it. The smoothest bow I've ever owned and shot. It has been very accurate, fast ( 290 fps w/ a 27" draw- chronoed!) and killed 3 does so far without a flaw.
I recently shot the new Hoyt Katera, and if this bow would have been around at the time I tried the others, I might have stayed with Hoyt and purchased the Katera. I do not regret the Drenalin at all. I expect it will last me for several years!