Sure it can. My first (and only) slug shotgun was the original typeIthaca Deerslayer. It was a 12-ga. smoothbore with the bore cut smaller so that the then-standard diameter (0.690") 12-ga. slugs being made in this country were a tight sliding fit in the bore. You might say it had a "13-ga." bore. With the Remington Foster-type 1-oz slugs which it really liked,that gun would shoot 3" groups at 100 yards. I had a 2.5X scope on it, and I never actually got to shoot it at a deer that far away. But if I had gotten such a shot, that gunwould have done the job.

To see if yours will, you need to try it. I assume you have sighting equipment on the gun which can let you shoot that far?? Get several brands of slugs, and test them until you find a load the gun likes. They will all shoot somewhat differently!