Did a canned hunt last year in NY State. All I had then was a 20 gauge Red Label. Used a one oz slug Buckhammer, and got a shot through the lungs on a nice 140 lb hog that was running. It went down and didn't move or make a sound. From 120 feet away in a treestand.
Just got a Rem 700 SPS in 300wsm. Would use that now, cause I got it! But that ounce of lead did the job last year. Use what you got, and place the shot!