I currently own two Mk V's and two Vanguards. I have used and reloaded for numerous Weatherby calibers from .257 up to the .378 and never been disappointed in accuracy or velocity. I have easily exceeded 3250fps with 180gr bullets in my .300, and 3350fps from a 24" barreled Vanguard in .270 with 130gr. Three shot groups are under 1" at that speed and no pressure signs.
Everyone has their likes and dislikes, and I sure have mine