With a 30-06, or any other 30 caliber cartridge, you can do it with a 180 grain bullet of proper construction and get much better in flightballistics than those big220 grain bullets.

Such as a 180 Barnes TSX will penetrate as well or better than a 200 0r 220 grain lead, round nosebullet. Or a Swift a-frame, Or a Winchester XP3, etc... etc...