I loaded up like 300 357 sigs in my crap Lee 1000. Well, you got to watch to make sure your hopper is at least 1/3 full. I forgot, and I knew I loaded up one or 2 without much powder or any. Long story sort, it pushed the bullet about 1" up a sig barrel.I was watching for it.I had to drive out with wooden dowl. Now a pistol cartidge like that has less room and more pressure primer alone, rifle, I doubt will do much.