Everyone seems to be making it a bigger issue than it is. Just as some use handguns or archery for hunting and it increases the challenge, .22 can be used for coyotes, it just makes it harder. If you want to find the ones you shoot you must make head shots, and at closer ranges than a high power would be capable of. For a more efficent coyote killing setup don't use a .22, but there is nothing wrong with using one if you use it properly.