My Ruger Super Redhawk is my most accurate revolver. It is more dificult to accurately shoot 454 ammo than 45Colt. Shooting 45 Colt thru it is less expensive plus there is not as much recoil.
I believe if you were to use a 357 for deer you would really have to limit yourself to closer distances.
Some find the looks of the Super Redhawk offensive especially after loosing an informal shooting contest to it