I have a .45 Hawken and have had good luck on deer using the T/C Maxi Hunters. They are a pre-lubed conical and I was pushing them with 110 gr. of Pyrodex RS. I also used a Wonder Wad (lubed) between the powder and the bullet. My only complaint with this load was that it printed a little higher on the first shot (clean barrel) as it did on subsequent shots. Even if I let it cool completely. So I sighted it in right on at 100 yards - knowing that it would hit 3" high on the first shot out of a clean barrel. Bullet will expand big time on deer. Good luck. Roskoe