Absolutely. Actually, I would only do timing by myself, as you may not be able to get the same type of grip with a machine.
Assuming you are able to press your bow to make cable ajustments, here is how I would do it:
First drawing the bow, get the cams balanced (synchronized) at full draw the best you can by eye (depending on the cam style, it may be easy or difficult. If one cam hits first shorten it's cable (or lengthenen the other) go either 1/2 or 1 twist at a time, as a little goes a long way.
Here is a link that will explain some of this vice me typing it:
http://www.merlin-bows.co.uk/balanci...our%20cams.htm
After you have the synchronization eyeballed as best you can, put a horizontal line (black tape works great) on your target at 20 yards and shoot srrow at the line drawing firmly to the wall. Then shoot some while creeping forward about 1/4" if they hit the same line, your timing is dead on; if the creep shots hit low,put a 1/2 twist in the cable connected to the top cam; if the creep shots hit hi, put 1/2 twist in the cablle attached to the bottom cam. MAKE VERY SMALL AJUSTMENTS, as it only takes a little.
Once you have it on, you can now go to 40 yards and try the same thing. Here make super fine adjustments (I recommend only using the split secion of the cables and adding 1/2 twists at this range.
Here is a link on this:
http://www.bowmanbows.com/creep.htm