RE: axle to axle
I think the critical measurement is cam position. Each manufacturer will have an ideal position for the cam(s). I would recommend finding what this position is for your bow, and adjusting string and/or cable lengths to meet this position.
After everything is perfect and bow is tuned, then take careful measurement of ata, brace heights, nock position and peep position (if you use one). Record these for the simple reason of easily getting back to the ideal shooting when you change your string or cables, or just to check it now and then to be sure things haven't changed.
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