Asuming your bow is in tune, follow Mobowhuntr's advice. If your bow isnt in tune/perfect arrow flight, you could be in for a treat trying to get it dialed in.
I'd take mobo's advice, then do "walk-back" tuning to insure your center shot is correct as well.
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Hoyt Avenger
Extreme RT900
QAD Ultra Pro
Carbon Exp. Term. Lite Hunter 27" 2" Blazers-Wrapped
Scott Little Goose
Muzzy 100gr. 4 Blade
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As Mobo say's follow the arrow ,,,shooting high raise the sight ,shooting low lower the sight ,,shooting left ,move thesight to the left ,and shooting right ,move to the right .