Historically they were bred to hunt lions in packs, tree them much like the hounds do to mountain lions here. Also to fend off all sorts of animals in Africa.
Nowadays I've heard of them being used for hogs, coons, mountain lions, and even to flush gamebirds.
I have heard of them being used for hogs now that you mention it. I really like the way they look. If I could have dog collection(wife says no way) I would want one.