Full power loads will take out a wolf or wolf sized animial with no problem at all. Also you can load it down for small game, as my friend and i use to do.
I swaged a lot of light weight bullets for my Hornet useing fired 22lr cases for the jackets! I'd push the jacket into the swage die "backwards", to make a "solid nose" and then we would use them on rabbits ect.. They also worked well in my 12 ga .222 combination gun too.
Another thing we use to do, useing a Lee hand loader. We took a fired case, pushed out the old primer, and then pushed in a new primer. Then we took a 22 cal. pellet, and pushed it HEAD FIRST into the neck of the Hornet case. (NO powder) "Instant" pellet rifle!!
I shot a lot of pest around my place with that combo, and there's not much noise either.
Drilling Man