RE: Bullet Damage...
Hi Canadian Hunter312,
I've got a feeling most bullets from either of those calibers will exit on broadside shots. The light bullets from the .22-250 might not if shooting "end to end", where as most bullets in any of the 6mm's probably will, (in case that matters?).
If there is a chance the rifle will be used on game heavier than "yotes" then I would choose the .243! But for your stated purposes either caliber should just about be the ticket.
Personally, I'd handle a number of different rifles...until I found one I liked....and could "get a good deal on".....and that's the one I'd buy. I doubt you'd be disappointed in either!
Good luck with your decision!
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