You betcha!
I built one on a rem 700 action a couple of winters ago. Its a jim dandy.

I've shot deer with mine and it is an absolute hammer of thor. My father has shot Red Stag, Himalayin tar, Chamois, Pronghorn, and deer with his. His comment was: "It kicks like a 243, flies like a 7 mag, and hits like a 338; I think I like it!"
One thing though, DO NOT build a 6.5-284 on a short action. If you load 140's you will not be able to chase the lands and utilize the magazine. My father discovered this, so I built mine on a long action.