RE: Best varmit rifle P.dogs to coyotes 223,22-250,222,243
If you'll be doing high volume shooting...go .223. 22-250 costs considerabley more and will "burn-out" a barrel much faster. Now, if you go up to the 243 in your subject title, you open the door to deer hunting  If you don't plan to put more than 100-200 rounds a year through the gun, you shouldn't worry about the 22-250 barrel.
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