i have used the 300gr speer hp loaded by federal with great sucess,switched to hornady just to try em,and they work but i think the hornady are a little overkill for whitetail and dont expand as fast as the speer hp.i even spoke with hornady about this and they stated the 325gr evolution bullet will work fine for deer but was designed more for larger game and deeper penetration and might not expand as rapidly as the federal round.i also think the 405gr is a little overkill for a whitetail but thats just my opinion