RE: 25-06 or 6.5x55?
For coyotes and varmints, the .25-06 is a great round, especially if you handload. I load mine with 75 gr. V-Max's, and they make some dandy coyote medicine. Not real easy on hides,though. Shoot very flat and fast, and buck wind pretty good. For larger game, it will handle bullets up to 120 grains.