RE: 22-250 vs 243 for coyote?
The 22-250 would sure get my vote for all around varmits including Yote size varmits. The 243 will do the job very well also but I prefer the 22-250. Less noise and recoil. Very accurate and shooter friendly. Out to 300 yards, the 223 will do the job cheaper than anything and nearly as well.